The samples of this research were 45 students of AnNizam grade VII. The instruments used in this study consisted of 1) questionnaire on the level of students' interest in science, 2) interview sheets, 3) Science Process Skills Test. The research method used in this study is descriptive and associative correlational survey research methods. This study aims to: 1) Determine the level of student interest in science lessons using a scientific approach, 2) Investigate the effect of the scientific approach on students' science process skill levels, 3) Investigate the relationship between interest in science lessons and science process skills. In this study, the learning process was carried out using a scientific approach, then measuring the students' interest in science lessons and science process skills.